Phenobarbital will reduce the extent or effect of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. lenacapavir will increase the stage or impact of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. primidone will lessen the extent or effect of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metab... https://thomasj655ugq7.wiki-cms.com/user