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DNA ligases seal five′-PO4 and 3′-OH polynucleotide ends by using three nucleotidyl transfer actions involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are essential guardians of genomic integrity, and ligase dysfunction underlies human genetic condition syndromes. Crystal buildings of DNA ligases certain to nucleotide and nucleic acid substrates have illuminated https://trevoraxsmf.boyblogguide.com/27590259/the-best-side-of-info-https-ligaz-bet

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