Reworked DLBCL usually include CDKN2A deletions and MYC translocations or amplifications in addition to the genomic alterations by now present in the first CLL, but lack the popular mutations observed in primary DLBCL indicating they might correspond to another biological classification.80 Richter transformation also happens in patients addressed with BTK https://subhashu233ztg1.nizarblog.com/profile