There's a launch of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors inside the dorsal horn to minimize afferent ache transmission and make analgesia. For that reason, medications like clonidine that concentrate on alpha-two receptors can influence the transmission of discomfort. This doc won't include all https://georgez691zvp0.eveowiki.com/user